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Slide 36 of 56
Mitochondrial DNA ( mtDNA) is a small amount
of DNA that is contained within the mitochondria (the chemical powerhouses
of the cell). Since only nuclear DNA is transferred from the sperm to
fertilize the egg, all the mtDNA comes from the mother.
One study analyzed mtDNA in 42 Mongolians from Ulan Bator.
All four Amerindian founding lineage haplotypes were detected in 54% of these
42 individuals, demonstrating an Asian origin.1
A second study examined mtDNA hypervariable segment I (HVS-1) from the Tuvinians and
Buryats, two aboriginal
populations of South Siberia. This study found that these populations expressed
the four Native American-specific
haplogroups (A-D) at frequencies of 72.2% and 55%.2
Another study, using 720 Amerindian
mtDNA sequences, showed that Native
Americans’ ancestral-population differentiation occurred approximately 22,000 years ago,3 well
before the time frame given in the Book of Mormon. Other studies have set the
date for the founding haplogroups at 34,000 years
ago.4 A study of mtDNA from 108 individuals from 700 year old burial site
confirmed the founding populations originated 23,000-37,000 years
ago.5
References
-
Merriwether DA, Hall WW, Vahlne A, Ferrell RE. 1996. mtDNA variation
indicates Mongolia may have been the source for the founding population for
the New World. Am J Hum Genet 59:204-212.
-
Derenko MV, Malyarchuk BA, Dambueva
IK, Shaikhaev GO, Dorzhu CM, Nimaev DD,
Zakharov IA. 2000. Mitochondrial DNA variation in two South Siberian
Aboriginal populations: implications for the genetic history of North Asia. Hum.
Biol.
72:945-973.
-
SL Bonatto and FM
Salzano. 1997. Diversity and Age of the
Four Major mtDNA Haplogroups, and Their Implications for the Peopling of the
New World. Am. J. Hum. Genet. 61:1413-1423.
-
YB Starikovskaya, RI
Sukernik, TG Schurr, AM Kogelnik,
and DC Wallace. 1998. mtDNA Diversity in Chukchi and Siberian
Eskimos: Implications for the Genetic History of Ancient Beringia and the
Peopling of the New World. Am. J. Hum. Genet. 63:1473-1491.
-
AC Stone and M
Stoneking. 1998. mtDNA Analysis of a
Prehistoric Oneota Population: Implications for the Peopling of the New World.
Am. J. Hum. Genet. 62:1153-1170.
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