Early Successes – Adult Stem Cells
- Human mesenchymal stem cells turned on genes found
in bone, cartilage, adipose, muscle, hematopoiesis-supporting
stromal, endothelial, and neuronal cells.
- Multipotent adult progenitor cells have been shown
to differentiate into functional, hepatocyte-like cells.
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Adult stem cells have shown
great promise in many published studies. These cells have shown the
potential to form many different kinds of cell types and tissues,
including functional hepatocyte-like (liver) cells. Such cells might be
useful in repairing organs ravaged by diseases.
References
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Tremain, N., et al., “MicroSAGE Analysis
of 2,353 Expressed Genes in a Single-Cell Derived Colony of
Undifferentiated Human Mesenchymal Stem Cells Reveals mRNAs of Multiple
Cell Lineages,” Stem Cells 19: 408-418 (2001).
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Schwartz, R. E., et al., “Multipotent
adult progenitor cells from bone marrow differentiate into functional
hepatocyte-like cells,” Journal of Clinical Investigation 109:
1291-1302 (2002).
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Last Modified July 6, 2004